Date
16 July 2019 (Day 1)
Place
Danubius, London
Present members
Professor Andrew Farmer (Chair)
Professor John Norrie (Deputy Chair)
Professor Hywel Williams (Programme Director)
Mr Alan Chant (PPI representative)
Mr Dave Green (PPI representative)
Professor Julie Brittenden
Miss Kirstin Carswell
Professor Mike Clarke
Professor Matt Costa
Professor Fay Crawford
Dr Jo Dumville
Professor Caroline Free
Professor Simon Gates
Professor Kerenza Hood
Professor Nick James
Professor Asma Khalil
Professor Steff Lewis
Dr Rumana Omar
Professor Rupert Pearse
Professor Mark Peters
Dr Matthew Ridd
Professor Christine Roffe
Dr Marc Serfaty
Dr Sarah Stock
Dr Sara Twaddle
NETSCC, HTA Secretariat
Dr Duncan Fortescue-Webb (Specialty Registrar in Public Health, NIHR)
Mr Kevin Campbell (Senior Research Manager)
Miss Louise Maclachlan (Research Manager)
Miss Louisa Saunders (Assistant Research Manager)
Apologies
Mrs Amanda Roberts
Dr Colin Green
Professor Craig Ramsay
Professor Olivia Wu
Professor Julia Lawton
Associate Professor Joanna Thompson-Coon
Observers
None
Quoracy Information
Voting members: 29 Quorum = 20
Voting members present on Day 1: 79%
Researcher-led Stage 2 Proposals
NIHR128513: A comprehensive model and economic evaluation of HCV elimination amongst people who inject drugs in England to guide case-finding intervention policy and implementation
(Professor Peter Vickerman, University of Bristol)
Chair: Andrew Farmer
Declared a conflict and left the room: Matthew Ridd, Caroline Free, Hywel Williams
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
NIHR128721: Pregnancy AntihyperteNsive Drugs: which Agent is best? (giant PANDA study)
(Professor Lucy Chappell, King's College London)
Chair: John Norrie
Declared a conflict and left the room: Andrew Farmer, Asma Khalil
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Pain Themed Call Stage 2 Proposals
NIHR128782: A systematic review with mixed treatment comparisons meta analysis of anti-depressant treatment for adults with chronic pain
(Professor Tamar Pincus, Royal Holloway, University of London)
Chair: John Norrie
Declared a conflict and left the room: Andrew Farmer
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Frailty Themed Call Stage 2 Proposals
NIHR128741: A randomised controlled trial of mobility training with or without protein supplementation to prevent or reverse frailty in community dwelling older people.
(Professor Sarah Lamb, University of Oxford)
Chair: John Norrie
Declared a conflict and left the room: Andrew Farmer, Matthew Costa, Simon Gates
Funding Committee recommendation: Decline
NIHR128334: Clinical and cost-effectiveness of a personalised health promotion intervention enabling independence in older people with mild frailty (‘HomeHealth’): A Randomised Controlled Trial
(Professor Kate Walters, University College London)
Chair: Andrew Farmer
Declared a conflict and left the room: Marc Serfaty, Hywel Williams, Rumana Omar
Left meeting: Mike Clarke
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
NIHR128862: Community-based complex interventions to sustain independence in older people, stratified by frailty: a systematic review and network meta-analysis
(Dr Andrew Clegg, University of Leeds)
Chair: Andrew Farmer
Declared a conflict and left the room: Fay Crawford, Jo Dumville, Hywel Williams, John Norrie
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Commissioned Stage 2 Proposals
18/98: Oral nutritional interventions in malnourished frail elderly
Chair: Andrew Farmer
Declared a conflict and left the room: none
NIHR128157: Oral nutritional interventions for malnourished, frail older people
(Professor Alison Avenell, University of Aberdeen)
Funding Committee recommendation: Decline
NIHR128729: Assessing the effectiveness and cost-effectiveness of oral nutritional interventions in malnourished frail elderly people
(Dr Sheena Ramsay, University of Newcastle upon Tyne)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
18/100: Strategies for the management of chronic constipation in childhood
Chair: Andrew Farmer
Declared a conflict and left the room: None
NIHR128470: Strategies Used for Constipation in Children - Evidence Synthesis involving Stakeholders (SUCCESS)
(Professor Doreen McClurg, Glasgow Caledonian University)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
18/134: Active case finding of coeliac disease
Chair: John Norrie
Declared a conflict and left the room: Jo Dumville, Matthew Ridd, Andrew Farmer, Hywel Williams, Kerenza Hood
NIHR129020: What is the optimum strategy for identifying adults and children with coeliac disease? A systematic review and economic models.
(Dr Penny Whiting, University of Bristol)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
NIHR128685: Cost-effectiveness of active case finding of coeliac disease in at-risk groups in primary care
(Dr Matthew Kurien, The University of Sheffield)
Funding Committee recommendation: Decline
18/102: Left ventricular assist devices as destination therapy for advanced heart failure
Chair: Andrew Farmer
Declared a conflict and left the room: Jo Dumville, Matthew Ridd, Nick James
NIHR129038: Left ventricular assist devices (LVAD) as destination therapy (DT) for advanced heart failure (HF)
(Dr Maria Pufulete, University of Bristol)
Funding Committee recommendation: Decline
NIHR128996: Left ventricular assist devices as destination therapy for advanced heart failure
(Dr David Moore, University of Birmingham)
Funding Committee recommendation: Prioritisation Oversight Committee to consider fund with changes
18/99: Lifestyle modification interventions in adults with learning disabilities
Chair: Andrew Farmer
Declared a conflict and left the room: Rumana Omar
NIHR128755: Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities.
(Dr Leanne Harris, University of Glasgow)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
NIHR128887: The clinical and cost-effectiveness of LifEstyle modifications in Adults with a leaRNing disability: a mixed studies review and convergent synthesis of quantitative and qualitative evidence. The LEARN Study.
(Professor Suzanne Richards, University of Leeds)
Funding Committee recommendation: Decline
18/101: Interventions for the management of perceptual disorders following stroke
Chair: Andrew Farmer
Declared a conflict and left the room: Fay Crawford, John Norrie, Steff Lewis, Sarah Stock
NIHR128829: Perceptual disorders after stroke InterventiON EvidencE Review (PIONEER): a scoping review and Cochrane Review revision and expansion
(Professor Marian Brady, Glasgow Caledonian University)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Date
17 July 2019 (Day 2)
Place
Danubius, London
Present members
Professor Andrew Farmer (Chair)
Professor Hywel Williams (Programme Director)
Mr Dave Green (PPI representative)
Professor Julie Brittenden
Miss Kirstin Carswell
Professor Mike Clarke
Professor Matt Costa
Professor Fay Crawford
Dr Jo Dumville
Professor Caroline Free
Professor Kerenza Hood
Professor Asma Khalil
Professor Steff Lewis
Dr Rumana Omar
Professor Rupert Pearse
Professor Mark Peters
Dr Matthew Ridd
Professor Christine Roffe
Dr Marc Serfaty
Dr Sarah Stock
Dr Sara Twaddle
NETSCC, HTA Secretariat
Dr Duncan Fortescue-Webb (Specialty Registrar in Public Health, NIHR)
Mr Kevin Campbell (Senior Research Manager)
Miss Louise Maclachlan (Research Manager)
Miss Louisa Saunders (Assistant Research Manager)
Apologies
Mrs Amanda Roberts
Dr Colin Green
Professor Craig Ramsay
Professor Olivia Wu
Mr Alan Chant
Professor Simon Gates
Professor Nick James
Professor Julia Lawton
Associate Professor Joanna Thompson-Coon
Professor John Norrie (Deputy Chair)
Observers
Katherine Cowan, JLA Senior Advisor
Quoracy Information
Voting members: 29 Quorum = 19
Voting members present on Day 2: 66%
Commissioned Stage 2 Proposals (continued)
18/104: Prevention and treatment of incontinence-associated dermatitis
Chair: Andrew Farmer
Declared a conflict and left the room: Matthew Ridd, Hywel Williams, Kerenza Hood, Michael Clarke, Rumana Omar
NIHR128434: Implementation of Incontinence Associated Dermatitis prevention guidance in care home and community settings: a feasibility study
(Professor Fiona Cowdell, Birmingham City University)
Committee recommendation: Decline
NIHR128865: PREVENTion and treatment of Incontinence-Associated Dermatitis (IAD) through optimising care: development and feasibility of the IAD Manual (PREVENT-IAD)
(Dr Sue Woodward, King's College London)
Committee recommendation: Programme Oversight Committee to consider fund with changes
NIHR Cross-Programme Commissioning – Stage 2 Digital call proposals
NIHR127773: Tele-opHthalmology-enablEd and ARtificial Intelligence-ready referral pathway for coMmunity optomEtry referralS of retinal disease: the HERMES study - a Cluster Randomised Superiority Trial with a linked Observational Diagnostic Accuracy Study
(Dr Konstantinos Balaskas, Moorfields Eye Hospital NHS Foundation Trust)
Chair: Andrew Farmer
Declared a conflict and left the room: none.
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Commissioned Stage 2 Proposals (continued)
18/103: Recurrent intra-articular corticosteroid injections in osteoarthritis
Chair: Hywel Williams
Declared a conflict and left the room: Matthew Ridd, Andrew Farmer, Rumana Omar
NIHR129011: RecUrrent Intra-articular Corticosteroid injections in Osteoarthritis; the RUbICOn study
(Mr Michael Whitehouse, University of Bristol)
Funding Committee recommendation: Programme Oversight Committee to consider fund with changes
Researcher-led Evidence Synthesis Stage 1 Proposals
NIHR129708: Safety and effectiveness of tranexamic acid in trauma and surgery in the NHS: An individual patient data meta-analysis
(Dr Katharine Ker, London School of Hygiene & Tropical Medicine)
Chair: Andrew Farmer
Declared a conflict and left the room: Caroline Free, Michael Clarke, Asma Khalil
Funding Committee recommendation: Shortlist
NIHR129742: Systematic Review and meta-analysis of clinical and cost effectiveness and feasibility of a UK extracorporeal cardiopulmonary resuscitation programme for out-of-hospital cardiac arrests
(Associate Professor Joyce Yeung, University Hospitals Birmingham NHS Foundation Trust)
Chair: Andrew Farmer
Declared a conflict and left the room: Rupert Pearse
Funding Committee recommendation: Decline
NIHR129715: Diet and physical activity in pregnancy to prevent gestational diabetes: Individual Participant Data (IPD) meta-analysis on the differential effects of interventions with economic evaluation
(Professor Shakila Thangaratinam, Queen Mary University of London)
Chair: Hywel Williams
Declared a conflict and left the room: Andrew Farmer, Fay Crawford, Jo Dumville, Sarah Stock, Asma Khalil
Funding Committee recommendation: Shortlist
NIHR129713: Effectiveness and cost-effectiveness of gynaecological surveillance for women with Lynch syndrome: systematic reviews and economic evaluation
(Dr Tristan Snowsill, University of Exeter)
Chair: Andrew Farmer
Declared a conflict and left the room: Jo Dumville
Funding Committee recommendation: Shortlist
NIHR129523: BEhavioural Weight Management: COMponents of Effectiveness (BE:COME)
(Dr Jennifer Logue, University of Glasgow)
Chair: Andrew Farmer
Declared a conflict and left the room: Julie Brittenden
Left meeting: Matt Costa
Funding Committee recommendation: Shortlist
Researcher-Led Primary Research Stage 1 proposals
NIHR129025: WrIst Physiotherapy Interventions in Trauma (WIPIT Study)
(Associate Professor Ben Ollivere, The University of Nottingham)
Chair: Rupert Pearse
Declared a conflict and left the room: Jo Dumville, Andrew Farmer, Hywel Williams, Michael Clarke
Funding Committee recommendation: Decline
Commissioned Stage 1 proposals
19/28: Endoscopic bipolar radiofrequency ablation for treating biliary obstruction caused by unresectable cancer
Chair: Andrew Farmer
Declared a conflict and left the room: none
NIHR129784: Endoscopic bipolar radiofrequency ablation for treating biliary obstruction caused by unresectable cancer - evidence synthesis.
(Dr John Leeds, The Newcastle Upon Tyne Hospitals NHS Foundation Trust)
Funding Committee recommendation: Shortlist
NIHR Cross-Programme Commissioning – Stage 1 Digital call proposals
NIHR128803: A Prospective Mixed Methods Study of the Effects of Measuring Adherence to Chest Physiotherapy in Cystic Fibrosis (SEARCH-CF)
(Dr Edward Nash, University Hospitals Birmingham NHS Foundation Trust)
Chair: Andrew Farmer
Declared a conflict and left the room: Hywel Williams
Funding Committee recommendation: Decline
NIHR129153: Telemedicine Screening for Retinopathy of Prematurity: A Clinical Study of Efficacy and Safety of Video grading to Still Image Grading with Health Economic Impact Assessment.
(Dr Susmito Biswas, Manchester University NHS Foundation Trust)
Chair: Andrew Farmer
Declared a conflict and left the room: none
Funding Committee recommendation: Decline
NIHR129255: DISSH: Evaluating Digital health Intervention Supporting young people who Self-Harm
(Dr Martina Di Simplicio, Imperial College London)
Chair: Andrew Farmer
Left the meeting: Hywel Williams
Funding Committee recommendation: Decline
NIHR129334: The effectiveness and cost-effectiveness of home-based active video gaming therapy vs. treatment as usual on motor function of children with cerebral palsy: a pragmatic multi-centre randomised controlled trial with embedded economic evaluation and parallel process evaluation
(Dr William Farr, Sussex Community NHS Trust)
Chair: Andrew Farmer
Declared a conflict and left the room: None
Funding Committee recommendation: Invite Resubmission
NIHR129248: Digital technologies for home monitoring glaucoma: a feasibility study.
(Dr Katie Gillies, University of Aberdeen)
Chair: Andrew Farmer
Declared a conflict and left the room: Julie Brittenden, Kerenza Hood, Michael Clarke
Funding Committee recommendation: Shortlist
Close of day 2