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HTA Funding Committee Public Minutes 15 March 2022

Contents

Published: 29 April 2022

Version: 1

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Meeting

HTA Funding Committee (General)

Day 1 - Tuesday 15th March 2022

Venue

Virtual Meeting via Microsoft Teams

Present Members

Professor Julia Brown (Chair)
Professor Rupert Pearse (Deputy Chair)
Professor Andrew Farmer (Programme Director)
Professor Matthew Costa
Dr Janet Deane (Committee Member Development Scheme Participant)
Associate Professor Laura Coates (Committee Member Development Scheme Participant)
Professor Jo Dumville
Professor Nick Francis
Professor Caroline Free
Professor Simon Gates
Mr David Green (Public Committee Member)
Professor Kerenza Hood
Professor Khalida Ismail
Dr David Keene
Professor Asma Khalil
Dr Stephanie MacNeill
Dr Hema Mistry
Professor Mark Peters
Professor Craig Ramsay
Mrs Amanda Roberts (Public Committee Member)
Dr Marta Soares
Associate Professor Jo Thompson-Coon
Dr Sara Twaddle
Dr Dawn-Marie Walker

Secretariat

Dr Simon Fraser (Consultant Advisor)
Cristina Lujan Barroso (Research Manager)
Kathy Tier (Research Manager)
Vicky Taylor (Assistant Director NETSCC, Applications & Funding)
Louisa Saunders (Assistant Research Manager)

Apologies

Dr Ashley Agus
Mr Matthew Moore (Public Committee Member)
Associate Professor Athanasios Saratzis
Professor Hashim Ahmed

Observers

Martin Simpson-Scott (NETSCC Monitoring Research Manager)
Irene Moreno-Millian (NETSCC Monitoring Assistant Research Manager)

Quoracy Information

Voting members: 24 = 16
Voting members present on Day 1: 23 (96%)

Stage 2 Applications

21/547

NIHR150755 - The NIHR FAST-Forward phase III randomised controlled trial of 1 week vs 3 weeks of curative whole breast radiotherapy in early breast cancer: 10 (Main trial) and 5 (Nodal Sub- Study) year outcomes (Adrian Brunt)

Chair: Julia Brown
Conflicts:
 Marta Soares
Decision: Programme Oversight Committee to consider fund with changes

21/509 Dementia

NIHR150071 - The clinical and cost effectiveness of internet-delivered self-help Acceptance and Commitment Therapy for family carers of people with dementia (iACT4CARERS): A randomised controlled trial with ethnically diverse family carers (Naoko Kishita)

Chair: Rupert Pearse
Conflicts: NONE
Decision: Programme Oversight Committee to consider fund with changes

21/510 NIHR NICE rolling call

NIHR150532 - Antiplatelet Secondary Prevention International Randomised trial after INtracerebral haemorrhaGe (ASPIRING): a pragmatic, randomised, parallel group, open, phase 3, international superiority trial (Rustam Salman)

Chair: Julia Brown
Conflicts: Dawn-Marie Walker
Left meeting: Stephanie MacNeill
Decision: Decline

21/541 Medication support interventions and strategies for people with learning disabilities

NIHR150687 - Medication support interventions and strategies for people with learning disabilities - a mixed methods evidence synthesis (Yen-Fu Chen)

Chair: Julia Brown
Conflicts: Hema Mistry
Arrived meeting: Stephanie MacNeill
Decision: Programme Oversight Committee to consider fund with changes

21/502 Osteoarthritis in older or frail people with multiple long-term conditions

NIHR150184 - PUNTS trial Pain relief Using Nerve Treatments for Shoulder arthritis (Stephen Gwilym)

Chair: Julia Brown
Conflicts: Kerenza Hood, Asma Khalil, Marta Soares, Andrew Farmer, David Keene, Matthew Costa, Hema Mistry, Laura Coates, Simon Gates
Decision: Decline

21/502 Osteoarthritis in older or frail people with multiple long-term conditions

NIHR150050 - Clinical and cost-effectiveness of a NICE-informed, person-centred, management programme for older adults with osteoarthritis (OA) and multiple long-term conditions: a multicentre, primary care, randomised, parallel-group, superiority trial: the PERSONA trial. (Emma Healey)

Chair: Rupert Pearse
Conflicts: Matthew Costa, Nick Francis, Kerenza Hood, Craig Ramsay, Joanna Thompson-Coon, Andrew Farmer, David Keene, Janet Deane, Hema Mistry, Dawn-Marie Walker, Simon Fraser, Julia Brown
Decision: Decline

21/502 Osteoarthritis in older or frail people with multiple long-term conditions

NIHR150083 - MulTI-domain Self-management in Older People wiTh OstEoarthritis and Multi-Morbidities (TIPTOE) (Kate Button)

Chair: Rupert Pearse
Conflicts: Matthew Costa, Nick Francis, Kerenza Hood, Craig Ramsay, Joanna Thompson-Coon, Andrew Farmer, David Keene, Janet Deane, Hema Mistry, Dawn-Marie Walker, Simon Fraser, Julia Brown
Decision: Programme Oversight Committee to consider fund with changes

21/502 Osteoarthritis in older or frail people with multiple long-term conditions

NIHR150592 - OPTIMISE: Osteoarthritis Package of care To Improve Multi-morbid older Individuals' Symptoms Effectively (Hamish Simpson)

Chair: Rupert Pearse
Conflicts: Matthew Costa, Nick Francis, Kerenza Hood, Craig Ramsay, Joanna Thompson-Coon, Andrew Farmer, David Keene, Janet Deane, Hema Mistry, Dawn-Marie Walker, Simon Fraser, Julia Brown
Decision: Decline

Stage 1 Applications

21/555 Health Technology Assessment Programme Researcher-led (evidence synthesis)

NIHR151630 - Non-surgical interventions for managing pelvic organ prolapse in women: a network meta-analysis and cost-effectiveness analysis (Eugenie Johnson)

Chair: Julia Brown
Conflicts: 
None
Decision:
Decline

21/555 Health Technology Assessment Programme Researcher-led (evidence synthesis)

NIHR151853 - Diagnostic strategies for suspected acute aortic syndrome (AAS): Systematic review, meta-analysis, decision-analytic modelling, and value of information analysis (Steve Goodacre)

Chair: Rupert Pearse
Conflicts: David Keene, Nick Francis
Decision: Shortlist

21/558 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call

NIHR150958 - PROTECT PRegnancy Outcomes using continuous glucose monitoring TEChnology in pregnant women with Type 2 diabetes: a multicentre randomised controlled trial (Helen Murphy)

Chair: Rupert Pearse
Conflicts: 
Julia Brown, Khalida Ismail, Janet Deane
Decision:
Shortlist

21/558 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call

NIHR151005 - Trabeculectomy against Preserflo Study (TAPS): A pragmatic randomised controlled trial comparing the effectiveness, safety and cost effectiveness of trabeculectomy against Preserflo MicroShunt in patients with medically uncontrolled glaucoma (Anthony King)

Chair: Julia Brown
Conflicts: Hema Mistry, Craig Ramsay, Kerenza Hood
Decision: Decline

21/558 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call

NIHR151230 - A randomised controlled trial assessing the clinical and cost-effectiveness of Endovascular vs. Open revascularisation in severe oCClusive aorto-iliac disease. The EVOCC trial. (Athanasios Saratzis)

Chair: Julia Brown
Conflicts:
Janet Deane, Stephanie MacNeill
Decision:
Shortlist

21/558 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call

NIHR151289 - Reduction of Surgical Site Infection by Novel interventions - A multi-arm, multi-stage RCT in Vascular Groin Wounds (ROSSINI-G) (Michael Wall)

Chair: Julia Brown
Conflicts:
Hema Mistry, Jo Dumville, Simon Gates
Decision:
Decline